Publications

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2022

  • Martin, L. J., Poulson, S. J., Mannan, E., Sivaselvachandran, S., Cho, M., Setak, F., & Chan, C. (2022). Altered nociceptive behavior and emotional contagion of pain in mouse models of autism. Genes, Brain and Behavior, 21(1), e12778–n/a. https://doi.org/10.1111/gbb.12778 [PDF]

  • Darvish-Ghane, S., Lyver, B., Facciol, A., Chatterjee, D., & Martin, L. J. (2022). Inflammatory Pain Alters Dopaminergic Modulation of Excitatory Synapses in the Anterior Cingulate Cortex of Mice. Neuroscience, 498, 249–259. https://doi.org/10.1016/j.neuroscience.2022.07.010 [PDF]

2021

  • Cho, C., Deol, H. K., & Martin, L. J. (2021). Bridging the Translational Divide in Pain Research: Biological, Psychological and Social Considerations. Frontiers in Pharmacology, 12, 603186–603186. https://doi.org/10.3389/fphar.2021.603186 [PDF]

  • Lidhar, N. K., Darvish-Ghane, S., Sivaselvachandran, S., Khan, S., Wasif, F., Turner, H., Sivaselvachandran, M., Fournier, N. M., & Martin, L. J. (2021). Prelimbic cortex glucocorticoid receptors regulate the stress-mediated inhibition of pain contagion in male mice. Neuropsychopharmacology (New York, N.Y.), 46(6), 1183–1193. https://doi.org/10.1038/s41386-020-00912-4 [PDF]

  • Michailidis, V., Lidhar, N. K., Cho, C., & Martin, L. J. (2021). Characterizing Sex Differences in Depressive-Like Behavior and Glial Brain Cell Changes Following Peripheral Nerve Injury in Mice. Frontiers in Behavioral Neuroscience, 15, 758251–758251. https://doi.org/10.3389/fnbeh.2021.758251 [PDF]

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2020

  • Darvish-Ghane, S., Quintana, C., Beaulieu, J.-M., & Martin, L. J. (2020). D1 receptors in the anterior cingulate cortex modulate basal mechanical sensitivity threshold and glutamatergic synaptic transmission. Molecular Brain, 13(1), 1–121. https://doi.org/10.1186/s13041-020-00661-x [PDF]

  • Poulson, S. J., Aldarraji, A., Arain, I. I., Dziekonski, N., Motlana, K., Riley, R., Holmes, M. M., & Martin, L. J. (2020). Naked mole-rats lack cold sensitivity before and after nerve injury. Molecular Pain, 16, 174480692095510–1744806920955103. https://doi.org/10.1177/1744806920955103 [PDF]

  • Poulson, SJ., Martin, LJ. 2020. Social communication and modulation of pain. In: Dynamics of pain. Eds. Robert Sorge. Great River Learning. Dubuque IA. [PDF]

  • Ramzan, F., Creighton, S. D., Hall, M., Baumbach, J., Wahdan, M., Poulson, S. J., Michailidis, V., Stefanelli, G., Narkaj, K., Tao, C. S., Khan, D., Steininger, J., Walters, B. J., Monks, D. A., Martin, L. J., & Zovkic, I. B. (2020). Sex-specific effects of the histone variant H2A.Z on fear memory, stress-enhanced fear learning and hypersensitivity to pain. Scientific Reports, 10(1), 14331–14331. https://doi.org/10.1038/s41598-020-71229-x [PDF]

  • Verma, V., Khoury, S., Parisien, M., Cho, C., Maixner, W., Martin, L. J.*, & Diatchenko, L.* (2020). The dichotomous role of epiregulin in pain. Pain (Amsterdam), 161(5), 1052–1064. https://doi.org/10.1097/j.pain.0000000000001792 [PDF]   *Co-senior authors. [Impact Factor = 5.56]*

  • Zhang, H., Lecker, I., Collymore, C., Dokova, A., Pham, M. C., Rosen, S. F., Crawhall-Duk, H., Zain, M., Valencia, M., Filippini, H. F., Li, J., D’Souza, A. J., Cho, C., Michailidis, V., Whissell, P. D., Patel, I., Steenland, H. W., Virginia Lee, W. J., Moayedi, M., Sterly, T. L., Bains. J. S., Stratton, J. A., Matyas, J. R., Biernaskie, J., Dubins, D., Vukobradovic, I., Bezginov, A., Flenniken, A. M., Martin, L. J., Mogil, J. S., & Bonin, R. P. (2021). Cage-lid hanging behavior as a translationally relevant measure of pain in mice. Pain (Amsterdam), 162(5), 1416–1425. https://doi.org/10.1097/j.pain.0000000000002127 [PDF]

2019

  • Becker, S., Bräscher, A. K., Bannister, S., Bensafi, M., Calma-Birling, D., Chan, R. C., Eerola, T., Ellingsen, D.-M., Ferdenzi, C., Hanson, J. L., Joffily, M., Lidhar, N. K., Lowe, L. J., Martin, L. J., Musser, E. D., Noll-Hussong, M., Olino, T. M., Pintos Lobo, R., & Wang, Y. (2019). The role of hedonics in the Human Affectome. Neuroscience and Biobehavioral Reviews, 102, 221–241. https://doi.org/10.1016/j.neubiorev.2019.05.003 [PDF]   *[Impact Factor = 9.440]*

  • Cho, C., Michailidis, V., Lecker, I., Collymore, C., Hanwell, D., Loka, M., Danesh, M., Pham, C., Urban, P., Bonin, R. P., & Martin, L. J. (2019). Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale. Scientific Reports, 9(1), 359–359. https://doi.org/10.1038/s41598-018-36897-w [PDF]   *[Impact Factor = 5.56]*

  • Martin, L. J., Acland, E. L., Cho, C., Gandhi, W., Chen, D., Corley, E., Kadoura, B., Levy, T., Mirali, S., Tohyama, S., Khan, S., MacIntyre, L. C., Carlson, E. N., Schweinhardt, P., & Mogil, J. S. (2019). Male-Specific Conditioned Pain Hypersensitivity in Mice and Humans. Current Biology, 29(2), 192–201.e4. https://doi.org/10.1016/j.cub.2018.11.030 [PDF]   *[Impact Factor = 9.97]​*

  • Parisien, M., Samoshkin, A., Tansley, S. N., Piltonen, M. H., Martin, L. J., El-Hachem, N., Dagostino, C., Allegri, M., Mogil, J. S., Khoutorsky, A., & Diatchenko, L. (2019). Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain. Pain (Amsterdam), 160(4), 932–944. https://doi.org/10.1097/j.pain.0000000000001471 [PDF]   *[Impact Factor = 5.56]*

  • Tansley, S. N., Macintyre, L. C., Diamond, L., Sotocinal, S. G., George, N., Meluban, L., Austin, J.-S., Coderre, T. J., Martin, L. J.*, & Mogil, J. S.* (2019). Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity. Pain (Amsterdam), 160(4), 784–792. https://doi.org/10.1097/j.pain.0000000000001454 [PDF]  *Co-corresponding authors. [Impact Factor = 5.56]*

2018

  • Cho, C., Michailidis, V., & Martin, L. J. (2018). Revealing brain mechanisms of mTOR-mediated translational regulation: Implications for chronic pain. Neurobiology of Pain, 4, 27–34. https://doi.org/10.1016/j.ynpai.2018.03.002 [PDF]   *[Impact Factor = 3.596]*

  • Sivaselvachandran, S., Acland, E. L., Abdallah, S., & Martin, L. J. (2018). Behavioral and mechanistic insight into rodent empathy. Neuroscience and Biobehavioral Reviews, 91, 130–137. https://doi.org/10.1016/j.neubiorev.2016.06.007 [PDF]   *[Impact Factor = 9.440]*

2017

  • Martin, L. J., Smith, S. B., Khoutorsky, A., Magnussen, C. A., Samoshkin, A., Sorge, R. E., Cho, C., Yosefpour, N., Sivaselvachandran, S., Tohyama, S., Cole, T., Khuong, T. M., Mir, E., Gibson, D. G., Wieskopf, J. S., Sotocinal, S. G., Austin, J. S., Meloto, C. B., Gitt, J. H., Sonenberg, N., Greenspan, J. D., Fillingim, R. B., Ohrbach, R., Slade, G. D., Knott, C., Dubner, R., Nackley, A. G., Ribeiro-da-Silva, A., Maixner, W., Zaykin, D. V., Mogil1, JS., & Diatchenko, L. (2017). Epiregulin and EGFR interactions are involved in pain processing. The Journal of Clinical Investigation, 127(9), 3353–3366. https://doi.org/10.1172/JCI87406 [PDF]   *[Impact Factor = 12.784]*

  • Tuttle, A. H., Tansley, S., Dossett, K., Tohyama, S., Khoutorsky, A., Maldonado-Bouchard, S., Stein, L., Gerstein, L., Crawhall-Duk, H., Pearl, R., Sukosd, M., Leger, P., Hardt, O. M., Yachnin, D., Austin, J.-S., Chan, C. M., Pooters, T., Groves, I., Martin, L. J., Gkogkas, C. G., & Mogil, J. S. (2017). Social propinquity in rodents as measured by tube co-occupancy differs between inbred and outbred genotypes. Proceedings of the National Academy of Sciences - PNAS, 114(21), 5515–5520. https://doi.org/10.1073/pnas.1703477114 [PDF]   *[Impact Factor = 9.423]*

2016

  • Khoutorsky, A., Sorge, R. E., Prager-Khoutorsky, M., Pawlowski, S. A., Longo, G., Jafarnejad, S. M., Tahmasebi, S., Martin, L. J., Pitcher, M. H., Gkogkas, C. G., Sharif-Naeini, R., Ribeiro-da-Silva, A., Bourque, C. W., Cervero, F., Mogil, J. S., & Sonenberg, N. (2016). eIF2α phosphorylation controls thermal nociception. Proceedings of the National Academy of Sciences - PNAS, 113(42), 11949–11954. https://doi.org/10.1073/pnas.1614047113 [PDF]   *[Impact Factor = 9.423]*

2015

  • Khoutorsky, A., Bonin, R. P., Sorge, R. E., Gkogkas, C. G., Pawlowski, S. A., Jafarnejad, S. M., Pitcher, M. H., Alain, T., Perez-Sanchez, J., Salter, E. W., Martin, L., Ribeiro-da-Silva, A., De Koninck, Y., Cervero, F., Mogil, J. S., & Sonenberg, N. (2015). Translational control of nociception via 4E-binding protein 1. eLife, 4. https://doi.org/10.7554/eLife.12002 [PDF]   *[Impact Factor = 9.32]*

  • Martin, L. J., Hathaway, G., Isbester, K., Mirali, S., Acland, E. L., Niederstrasser, N., Slepian, P. M., Trost, Z., Bartz, J. A., Sapolsky, R. M., Sternberg, W. F., Levitin, D. J., & Mogil, J. S. (2015). Reducing Social Stress Elicits Emotional Contagion of Pain in Mouse and Human Strangers. Current Biology, 25(3), 326–332. https://doi.org/10.1016/j.cub.2014.11.028 [PDF]   *[Impact Factor = 9.97]*

  • Martin, L. J., Piltonen, M. H., Gauthier, J., Convertino, M., Acland, E. L., Dokholyan, N. V., Mogil, J. S., Diatchenko, L., & Maixner, W. (2015). Differences in the Antinociceptive Effects and Binding Properties of Propranolol and Bupranolol Enantiomers. The Journal of Pain, 16(12), 1321–1333. https://doi.org/10.1016/j.jpain.2015.09.004 [PDF]

  • Segall, S. K., Shabalina, S. A., Meloto, C. B., Wen, X., Cunningham, D., Tarantino, L. M., Wiltshire, T., Gauthier, J., Tohyama, S., Martin, L. J., Mogil, J. S., & Diatchenko, L. (2015). Molecular genetic mechanisms of allelic specific regulation of murine Comt expression. Pain (Amsterdam), 156(10), 1965–1977. https://doi.org/10.1097/j.pain.0000000000000258 [PDF]   *[Impact Factor = 5.84]*

  • Sorge, R. E., Mapplebeck, J. C. S., Rosen, S., Beggs, S., Taves, S., Alexander, J. K., Martin, L. J., Austin, J.S., Sotocinal, S. G., Chen, D., Yang, M., Shi, X. Q., Huang, H., Pillon, N. J., Bilan, P. J., Tu, Y., Klip, A., Ji, R.R., Zhang, J., Salter, M.W., & Mogil, J. S. (2015). Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nature Neuroscience, 18(8), 1081–1083. https://doi.org/10.1038/nn.4053 [PDF]   *[Impact Factor = 16.095]

  • Wieskopf, J. S., Mathur, J., Limapichat, W., Post, M. R., Al-Qazzaz, M., Sorge, R. E., Martin, L. J., Zaykin, D. V., Smith, S. B., Freitas, K., Austin, J.-S., Dai, F., Zhang, J., Marcovitz, J., Tuttle, A. H., Slepian, P. M., Clarke, S., Drenan, R. M., Janes, J., Al Sharari, S., Segall, S. K., Aasvang, E. K., Lai, W., Bittner, R., Richards, C. I., Slade, G. D., Kehlet, H., Walker, J., Maskos, U., Changeux, J. P., Devor, M., Maixner, W., Diatchenko, L., Belfer, I., Dougherty, D. A., Su, A. I., Lummis, S. C., Imad Damaj, M., Lester, H. A., Patapoutian, A., & Mogil, J. S. (2015). The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine, 7(287). https://doi.org/10.1126/scitranslmed.3009986 [PDF]   *[Impact Factor = 14.41]*

2014

  • Sorge, R. E.*, Martin, L. J.*, Isbester, K. A., Sotocinal, S. G., Rosen, S., Tuttle, A. H., Wieskopf, J. S., Acland, E. L., Dokova, A., Kadoura, B., Leger, P., Mapplebeck, J. C., McPhail, M., Delaney, A., Wigerblad, G., Schumann, A. P., Quinn, T., Frasnelli, J., Svensson, C. I., Sternberg, W. F., & Mogil, J. S. (2014). Olfactory exposure to males, including men, causes stress and related analgesia in rodents. Nature methods, 11(6), 629–632. https://doi.org/10.1038/nmeth.2935 [PDF]   *equal contributions [Impact Factor = 25.953]

2013

  • Whissell, P. D., Eng, D., Lecker, I., Martin, L. J., Wang, D.-S., & Orser, B. A. (2013). Acutely increasing δGABA(A) receptor activity impairs memory and inhibits synaptic plasticity in the hippocampus. Frontiers in Neural Circuits, 7, 146–146. https://doi.org/10.3389/fncir.2013.00146 [PDF]

2011

  • Martin, L. J., Zurek, A. A., Bonin, R. P., Oh, G. H., Kim, J. H., Mount, H. T., & Orser, B. A. (2011). The sedative but not the memory-blocking properties of ethanol are modulated by α5-subunit-containing γ-aminobutyric acid type A receptors. Behavioural brain research, 217(2), 379–385. https://doi.org/10.1016/j.bbr.2010.11.008 [PDF]

  • Sotocina, S. G., Sorge, R. E., Zaloum, A., Tuttle, A. H., Martin, L. J., Wieskopf, J. S., Mapplebeck, J. C., Wei, P., Zhan, S., Zhang, S., McDougall, J. J., King, O. D., & Mogil, J. S. (2011). The Rat Grimace Scale: A Partially Automated Method for Quantifying Pain in the Laboratory Rat via Facial Expressions. Molecular Pain, 7(1), 55–55. https://doi.org/10.1186/1744-8069-7-55 [PDF]

2010

  • Cheung, K. W., Lado, W. E.S., Martin, L., St-Pierre, L. S., & Persing, M. (2010). Cerebral Neurons in Rattus norvegicus Following a Mild Impact to the Skull: Equivalence of Modulation by Post-Impact Pregnancy or Exposure to Physiologically-Patterned Magnetic Fields. Journal of Biological Sciences (Faisalabad, Pakistan), 10(2), 84–92. https://doi.org/10.3923/jbs.2010.84.92 [PDF]

  • Martin, L. J., Zurek, A. A., MacDonald, J. F., Roder, J. C., Jackson, M. F., & Orser, B. A. (2010). α5GABAA Receptor Activity Sets the Threshold for Long-Term Potentiation and Constrains Hippocampus-Dependent Memory. The Journal of Neuroscience, 30(15), 5269–5282. https://doi.org/10.1523/JNEUROSCI.4209-09.2010 [PDF]   *[Impact Factor = 7.12]*

  • Saab, B. J., Maclean, A. J., Kanisek, M., Zurek, A. A., Martin, L. J., Roder, J. C., & Orser, B. A. (2010). Short-term memory impairment after isoflurane in mice is prevented by the α5 γ-aminobutyric acid type A receptor inverse agonist L-655,708. Anesthesiology, 113(5), 1061–1071. https://doi.org/10.1097/ALN.0b013e3181f56228 [PDF]   *[Impact Factor = 6.168]*

  • Vargas-Caballero M, Martin LJ, Salter MW, Orser BA, & Paulsen O. alpha5 Subunit-containing GABA(A) receptors mediate a slowly decaying inhibitory synaptic current in CA1 pyramidal neurons following Schaffer collateral activation. Neuropharmacology. 2010 Mar;58(3):668-75. doi: 10.1016/j.neuropharm.2009.11.005. Epub 2009 Nov 23. PMID: 19941877; PMCID: PMC2814005. [PDF]   *[Impact Factor = 5.106]*

2009

  • Martin, L. J., Bonin, R. P., & Orser, B. A. (2009). The physiological properties and therapeutic potential of α5-GABAA receptors. Biochemical Society Transactions, 37(6), 1334–1337. https://doi.org/10.1042/BST0371334 [PDF]

  • Martin, L. J., Oh, G. H. T., & Orser, B. A. (2009). Etomidate targets alpha5 gamma-aminobutyric acid subtype A receptors to regulate synaptic plasticity and memory blockade. Anesthesiology (Philadelphia), 111(5), 1025–1035. https://doi.org/10.1097/ALN.0b013e3181bbc961 [PDF]   *[Impact Factor = 6.168]*

  • Sun, H. S., Jackson, M. F., Martin, L. J., Jansen, K., Teves, L., Cui, H., Kiyonaka, S., Mori, Y., Jones, M., Forder, J. P., Golde, T. E., Orser, B. A., Macdonald, J. F., & Tymianski, M. (2009). Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. Nature neuroscience, 12(10), 1300–1307. https://doi.org/10.1038/nn.2395 [PDF]   *[Impact Factor = 14.976]*

2007

  • Bonin, R. P., Martin, L. J., MacDonald, J. F., & Orser, B. A. (2007). α5GABA sub(A) Receptors Regulate the Intrinsic Excitability of Mouse Hippocampal Pyramidal Neurons. Journal of Neurophysiology, 98(4), 2244–2254. [PDF]

2006

2005

  • Macdonald, D. S., Weerapura, M., Beazely, M. A., Martin, L., Czerwinski, W., Roder, J. C., Orser, B. A., & MacDonald, J. F. (2005). Modulation of NMDA receptors by pituitary adenylate cyclase-activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src. The Journal of neuroscience: the official journal of the Society for Neuroscience, 25(49), 11374–11384. https://doi.org/10.1523/JNEUROSCI.3871-05.2005 [PDF]   *[Impact Factor = 7.12]*

  • Martin, L. J., Koren, S. A., & Persinger, M. A. (2005). Thermal Analgesic Effects from Weak, Complex Magnetic Fields: Critical Parameters. Electromagnetic Biology and Medicine, 24(2), 65–85. https://doi.org/10.1080/15368370500205399 [PDF]

  • Martin, L. J., & Persinger, M. A. (2005). The Influence of Various Pharmacological Agents on the Analgesia Induced by an Applied Complex Magnetic Field Treatment: A Receptor System Potpourri. Electromagnetic Biology and Medicine, 24(2), 87–97. https://doi.org/10.1080/15368370500205431 [PDF]

2004

  • Galic, M. A., Fournier, N. M., & Martin, L. J. (2004). Alpha2-adrenergic inhibition prevents the accompanied anticonvulsant effect of swim stress on behavioral convulsions induced by lithium and pilocarpine. Pharmacology, biochemistry, and behavior, 79(2), 309–316. https://doi.org/10.1016/j.pbb.2004.08.003 [PDF]

  • Martin, L. J., Fournier, N. M., Galic, M. A., & Emond, M. H. (2004). Chronic administration of the L-type calcium channel blocker nimodipine can facilitate the acquisition of sequence learning in a radial-arm maze. Behavioural Pharmacology, 15(2), 133–139. https://doi.org/10.1097/00008877-200403000-00005 [PDF]

  • Martin, L. J., Koren, S. A., & Persinger, M. A. (2004). Influence of a complex magnetic field application in rats upon thermal nociceptive thresholds: The importance of polarity and timing. International Journal of Neuroscience, 114(10), 1259–1276. https://doi.org/10.1080/00207450490475689 [PDF]

 

  • Martin, L. J., Koren, S. A., & Persinger, M. A. (2004). Thermal analgesic effects from weak, complex magnetic fields and pharmacological interactions. Pharmacology, biochemistry, and behavior, 78(2), 217–227. https://doi.org/10.1016/j.pbb.2004.03.016 [PDF]

 

  • Martin, L. J., & Persinger, M. A. (2004). Thermal analgesia induced by 30-min exposure to 1 micro-T burst-firing magnetic fields is strongly enhanced in a dose-dependent manner by the alpha2 agonist clonidine in rats. Neuroscience Letters, 366(2), 226–229. [PDF]

2003

  • Martin, L. J., & Persinger, M. A. (2003). Spatial Heterogeneity Not Homogeneity of the Magnetic Field during Exposures to Complex Frequency-Modulated Patterns Facilitates Analgesia. Perceptual and Motor Skills, 96(3), 1005–1012. https://doi.org/10.2466/pms.2003.96.3.1005 [PDF]

2002